• Influence of the Integral Quality Monitor transmission detector on high energy photon beams: A multi-centre study

    This article discusses the influence of the Integral Quality Monitor (IQM) transmission detector on photon beam properties. The authors evaluated data acquired at nine different Radiation Therapy centers and concluded that the magnitudes of changes observed justify treating IQM either as energy-specific tray factors in the treatment planning system or alternatively as a set of modified output factors for each linac energy. Download this article for some valuable guidance for implementing the IQM System into your clinical routine.

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  • Integrating the IQM into a commercial planning system

    Bruce Perrin and his colleagues at the Christie Hospital investigated potential challenges when integrating IQM into a commerical planning system. They compared data measured in a waterphantom with and without the IQM detector for varioius energies (6,10 & 6FFF). They evaluated the IQM data against clinical models in Pinnacle 9.8 and analyzed the magnitude of deviations assessed. And finally, they verified their analytical results by delivering various treatment plans to the Delta 4 through IQM. Download the full presentation as shown during the ESTRO35 Conference in Turin, Italy in May 2016.

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  • The physics behind the IQM Signal

    Robert Heaton from the Princess Margaret Cancer Centre in Toronto, Canada presented the calculation model of the IQM System in terms of the physical characteristics and behavior of linear accelerators at the ESTRO36 Conference in Vienna, Austria in May 2017.

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  • Signal Prediction for an On-line Delivery Verification System

    Robert Heaton and his colleagues at the Princess Margaret Cancer Centre in Toronto developed a calculation method to predict the measured IQM signal for clinical IMRT fields. This poster was presented at the ESTRO36 conference in Vienna, Austria in May 2017.

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  • An integral quality monitoring system for real-time verification of intensity modulated radiation therapy

    Download the publication by the IQM project team at the Princess Margaret Hospital, Toronto. This article was published in 2009 as a proof of concept for the IQM system.

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  • Real-time beam monitoring for error detection in IMRT plans and impact on dose-volume histograms

    This multi-center study by Livia Marazzo, published in the German Journal of Radiation Therapy and Oncology tests the sensitivity of the Integral Quality Monitor (IQM) transmission detector for online dose monitoring of IMRT treatment techniques to detect small delivery errors. The article furthermore investigated the correlation between changes in the IQM signal, induced by small delivery errors, with other metrics like Gamma passing rate and dose-volume histogram metrics.  Download this article to learn about the high sensitivity of the IQM transmission detector for small delivery errors as well as the good correlation between the IQM detector signal and DVH metrics.

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  • Sensitivity Analysis of the Integral Quality Monitoring System using Monte Carlo Simulation

    Oluwaseyi M. Oderinde and his colleagues at the University of the Free State in Bloemfontein, South Africa evaluated the sensitivity of the IQM System to errors in beam segments using EGSnrc/BEAMnrc Monte Carlo (MC) codes. The authors show the potential of the IQM System to detect small segment alterations. This article was published in "Computational and Mathematical Methods in Medicine", Vol. 2017 and shows the error sensitivity of the IQM System during online beam monitoring.

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  • Real-time verification of VMAT delivery by an automated beam monitoring system

    Makan Farrokhkish and his colleagues at the Princess Margaret Cancer Centre evaluated the beam monitoring performance of the IQM System to assess the accuracy and reproducibility of the linac beam delivery. The signal calculation accuracy and measurement reproducibility as well as the error detection capability of the IQM System was evaluated. For this study the author analyzed 52800 beam segments. Download the poster that was presented at the AAPM 2017 conference in Denver.

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  • Online dosimetry with the Integral Quality Monitor

    Kilian Michel and his colleagues at the Lake Constance Radiation Oncology Center in Friedrichshafen, Germany evaluated the IQM System for Online Dosimetry during the patient treatment. The y checked the long-term signal stability, the error detection sensitivity for induced errors, the correlation of the IQM and the Dose-Volume-Histogram as well as treatment plan verification with the IQM System.

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  • Initial Evaluation of the Integral Quality Monitor (IQM)

    Mr. Bruce Perrin, Medical Physicist from The Christie Hospital in Manchester validated the effectiveness and reliability of the IQM in monitoring the correct delivery of daily fractions. The presentation was given at the 2015 UKRO (United Kingdom Radiation Oncology) Conference in Birmingham, UK.

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  • Online quality assurance of external beam radiation therapy with an integrated quality monitoring system

    David Hoffman, PhD at UC Davis evaluated the stability and accuracy of each feature of the IQM. This thorough review includes many comparative and illustrative graphics, and validated the IQM against its stated performance requirements and the site’s clinical standards. Download the full presentation given at the AAPM 2015 Meeting in Anaheim, CA.

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  • In Vivo Dosimetry of Conventional and Rotational Intensity Modulated Radiotherapy Using Integral Quality Monitor (IQM)

    Lan Lin, Medical Physicist at Johns Hopkins University evaluated the accuracy,sensitivity and constancy of the IQM for conventional intensity modulated radiationtherapy (IMRT) and for rotational volumetric modulated arc therapy (VMAT). Download the complete poster that was shown.at the AAPM 2015 Meeting in Anaheim, CA.

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  • Testing IQM: A system for real-time monitoring of complex radiotherapy treatments

    Stefania Pallotta from University of Florence, Italy evaluated the IQM during pre-clinical testing. She concludes that IQM provides optimal performance for signal reproducibility for complex IMRT plans. Her work demonstrated that IQM is capable of detecting small errors in MU and leaf positions and is sufficient for clinical practice. Download the complete poster that was shown at the IEEE conference in Milano, Italy

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  • In-Vivo Dosimetry of Stereotactic Radiation Therapy using the IQM System

    Jianguo Qian from the Johns Hopkins University, Baltimore draws the preliminary conclusion that IQM is a stable dosimetric system and can detect dosimetric deviations caused by small leaf errors in stereotactic radiation therapy. The sensitivity to leaf errors was demonstrated to be more pronounced for relatively small fields (i.e., small targets) in SBRT. IQM appears to be more sensitive than Mapcheck2 to small leaf errors in SBRT of small targets while showing similar sensitivity in SBRT of relatively large targets. Download the complete poster that was shown at the ASTRO 57 meeting in San Antonio, Texas.

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  • Reproducibility and sensitivity of IQM: A real-time monitoring device for complex radiotherapy treatments

    Chiara Arilli, Cinzia Talamonti, Livia Marrazzo and their colleagues from the AOU Careggi, Florence, Italy evaluated the output signal reproducibility and sensitivity in detecting small errors in delivery parameters of step and shoot IMRT treatments with the IQM System.  The team also assessed the correlation between IQM signal variations and 3Dγ, 2Dγ and DVH parameters. Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.

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  • Pre-clinical tests of the IQM System

    Marlies Pasler and her colleagues at the Lake Constance Radiation Oncology Center in Friedrichshafen, Germany investigated the potential of the IQM System to catch errors before they become clinically relevant. They also examined whether IQM would help them to improve the efficiency of their processes and finally they assessed whether IQM could successfully replace their current pre-treatment QA. They concluded that IQM could improve the efficiency of their workflow and that its error detection capabilities are sufficient for clinical practice. Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.

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  • Delivery errors detectability with IQM, a system for real-time monitoring of radiotherapy treatments

    Livia Marrazzo and her colleagues at the AOU Careggi in Florence evaluated the correlation between changes in the detector output signal induced by small delivery errors with other metrics, such as the Gamma pass rate and DVH variations. They concluded that IQM is capable of detecting small delivery errors and that it exhibits a good correlation with other metrics currently used to determine the quality of a treatment plan. Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.

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  • Real-time detection of deviations in radiotherapy beam delivery using a head-mounted detector

    Martijn Kusters from Radboud UMC, Nijmegen, The Netherlands states that IQM enables a clinic to do real-time, intra-fraction monitoring of beam delivery. The error sensitivity and specificity can be expected to be sufficient for clinical practice, and performs at least as well as their current equipment (Scandidos Delta 4). Download the full presentation given at the iRT booth during the ASTRO 57 meeting in San Antonio, Texas in 2015.

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  • Efficient and Enhanced QA Testing of Linear Accelerators using a Real-time Beam Monitor

    Mr. Andrew Jung. (Member of the IQM development team at the Princess Margaret Cancer Centre in Toronto) evaluated the possibility to utilize the IQM system for a variety of Linac QA purposes. Download the full presentation that was given at the iRT booth during the AAPM 2015 meeting in Anaheim, CA.

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  • A new wedge-shaped ionization chamber component module for BEAMnrc to model the IQM system

    Oluwaseyi Michael Oderinde and his colleagues at the University of the Free State in Bloemfontein, South Africa developed a new component module (CM) to accurately model the integral quality monitoring (IQM) system to be used in the BEAMnrc Monte Carlo (MC) code. Download this publication in "Radiation Physics and Chemistry", which serves as a basis for researchers that have an interest in MC study of wedge-shaped ionization chamber systems.

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  • Monte Carlo Study of an Integral Quality Monitoring (IQM) System

    Oluwaseyi Oderinde from the University of the Free State, South Africa modelled the IQM using the BEAMnrc component module. this model stands as a basis for Monte Carlo study of the IQM system. Download the complete poster that was shown at the SAAPMB conference in Bloemfontein, South Africa.

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  • IQM Detector Characteristics: Signal Linearity and Dose Rate (In-) Dependence (White Paper)

    IQM has been thoroughly evaluated at some of the world’s leading Radiation Therapy Centers. The signal linearity test verifies that the signal detected by IQM is directly proportional to the dose output. The dose rate dependence test verifies that the IQM system measures the same signal for the same dose independent of the
    dose rate at which the dose is delivered. Download the IQM White paper to learn about the exceptional signal linearity and dose rate independence of the IQM system.

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  • IQM Detector Characteristics: Signal reproducibility (White Paper)

    IQM has been thoroughly evaluated at some of the world’s leading Radiation Therapy Centers. A variety of acceptance tests were performed as part of the installation routine at every clinical center. Download the IQM White paper to learn about the exceptional signal reproducibility of the IQM system.

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  • Online dosimetry with the Integral Quality Monitor

    Kilian Michel and his colleagues at the Lake Constance Radiation Oncology Center in Friedrichshafen, Germany evaluated the IQM System for Online Dosimetry during the patient treatment. The y checked the long-term signal stability, the error detection sensitivity for induced errors, the correlation of the IQM and the Dose-Volume-Histogram as well as treatment plan verification with the IQM System.

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  • Quality Assurance with the IQM system - the Radboud UMC experience

    Richard Canters from Radboud UMC in Nijmegen, The Netherlands evaluated the error detection capability of the IQM System. He found out that IQM detects small errors in beam delivery with respect to pre-calculated beams, detects small errors during a treatment course with respect to reference beams, and further, that IQM operates with almost no user interaction necessary and it closes the TPS – R&V – Linac circle. Download the full presentation that was given at the iRT booth during the 3rd ESTRO Forum in Barcelona, Spain in April 2015.

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  • Preliminary tests with the IQM system - the University of Florence experience

    Stefania Pallotta states that IQM provides an optimal performance for IMRT QA, based on the results of this study, which saw intra-fractional standard deviation (%STD) of 0.04% and inter-fractional %STD of up to 0.36% for complex IMRT cases over a period of multiple weeks. Download the full presentation that was held at the iRT booth during the 3rd ESTRO Forum in Barcelona, Spain

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  • Pre-clinical tests of the IQM System

    Marlies Pasler and her colleagues at the Lake Constance Radiation Oncology Center in Friedrichshafen, Germany investigated the potential of the IQM System to catch errors before they become clinically relevant. They also examined whether IQM would help them to improve the efficiency of their processes and finally they assessed whether IQM could successfully replace their current pre-treatment QA. They concluded that IQM could improve the efficiency of their workflow and that its error detection capabilities are sufficient for clinical practice. Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.

    Download Document
  • Delivery errors detectability with IQM, a system for real-time monitoring of radiotherapy treatments

    Livia Marrazzo and her colleagues at the AOU Careggi in Florence evaluated the correlation between changes in the detector output signal induced by small delivery errors with other metrics, such as the Gamma pass rate and DVH variations. They concluded that IQM is capable of detecting small delivery errors and that it exhibits a good correlation with other metrics currently used to determine the quality of a treatment plan. Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.

    Download Document
  • Real-time detection of deviations in radiotherapy beam delivery using a head-mounted detector

    Martijn Kusters from Radboud UMC, Nijmegen, The Netherlands states that IQM enables a clinic to do real-time, intra-fraction monitoring of beam delivery. The error sensitivity and specificity can be expected to be sufficient for clinical practice, and performs at least as well as their current equipment (Scandidos Delta 4). Download the full presentation given at the iRT booth during the ASTRO 57 meeting in San Antonio, Texas in 2015.

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  • Characterization and evaluation of an integrated quality monitoring system for online quality assurance of external beam radiation therapy

    This comprehensive evaluation of the new large field ion chamber transmission detector, Integral Quality Monitor (IQM) addresses  online external photon beam verification and quality assurance. Download the complete JACMP publication.

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  • An integral quality monitoring system for real-time verification of intensity modulated radiation therapy

    Download the publication by the IQM project team at the Princess Margaret Hospital, Toronto. This article was published in 2009 as a proof of concept for the IQM system.

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  • Response Characteristics of a Large-Area Ion Chamber with Various Radiotherapy Beams

    Download the full presentation about the response characteristics of the IQM system with different beams. This presentation was given by Mr. Makan Farrokhkish, B.Sc. (Member of the IQM development team) at the World Congress on Medical Physics & Biomedical Engineering 2015 in Toronto.

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  • Performance Study of an automated real-time monitoring system for SBRT treatments

    Makan Farrokhkish from the Princess Margaret Cancer Centre, Toronto states that IQM is well suitable to verify state-of-the-art SBRT treatments utilizing FFF Rapid Arc treatments on a Varian TrueBeam linear accelerator. Download the full presentation that was given at the iRT booth during the ASTRO 57 conference in San Antonio, Texas.

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  • IMRT Plan QA with the IQM detector

    Sonja Wegener and her colleagues from the University of Würzburg, Germany evaluated the IQM System for IMRT plan QA. The team validated the IQM Calculation algorithm for a wide spectrum of clinical IMRT cases. They then tested the error sensitivity of the IQM System with a variety of induced errors, and compared the error detection capability of the IQM System against their current IMRT QA approaches. The IQM found all the errors detected by their current IMRT approaches and detected several errors that were missed by the other techniques.

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  • Beam Delivery Check and In-Vivo Dosimetry during Breast Radiotherapy Treatment

    Cinzia Talamonti and her colleagues from the University of Florence, Italy verified the delivery of the prescribed dose during radiotherapy treatment using the IQM in combination with portal imaging, together with the software SoftDiso (Best Medical Italy Srl) for in-vivo measurements. They evaluated the ability of detecting positional and delivery errors intentionally introduced during breast treatments. Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.

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  • Evaluation of an Integral Quality Monitor device for monitoring real-time delivery

    Gloria Miori, Andrea Martignano and their colleagues from Azienda Provinciale per i Servizi Sanitari in Trento, Italy analyzed the use of the IQM System for real-time beam delivery control. They evaluated the IQM's beam attenuation and it's ability to detect VMAT delivery errors. They concluded that the IQM beam attenuation can be considered homogenous in both X and Y directions and that the machine-specific beam attenuation percentage could be used to rescale treatment plan dose for clinical IQM use. They noted that the IQM shows appreciable features in detecting real-time errors and in time-saving QA. Download the full poster that was shown during the AIFM Conference in Perugia, Italy in February 2016.

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  • Real-time detection of deviations in radiotherapy beam delivery using a head-mounted detector

    Martijn Kusters from Radboud UMC, Nijmegen, The Netherlands states that IQM enables a clinic to do real-time, intra-fraction monitoring of beam delivery. The error sensitivity and specificity can be expected to be sufficient for clinical practice, and performs at least as well as their current equipment (Scandidos Delta 4). Download the full presentation given at the iRT booth during the ASTRO 57 meeting in San Antonio, Texas in 2015.

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  • Verifying Total Body Irradiation using the IQM System

    Gabriele Guidi and his colleagues from Az. Ospedaliero Universitaria di Modena evaluated the use of IQM for the verification of TBI treatments. They investigated the influence of the IQM Detector on depth dose curves and beam profiles for an extended SSD of 170cm. The presentation outlines the considerations that should be applied when utilizing IQM for TBI verification. They concluded that IQM can be used for TBI verifcation. Download the full presentation that was shown during the ESTRO35 Conference in Turin, Italy in May 2016.

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